MYOCARDIALFIBROSIS相关论文
Objective: The purpose of this study is to evaluate the potential utility of MRI native EPI-T1 mapping based on myocardi......
Assessment of diabetic cardiomyopathy by cardiovascular magnetic resonance T1 mapping:Correlation wi
Aims Diabetic cardiomyopathy is accompanied by left-ventricular impaired diastolic function but preserved systolic funct......
Prognostic Value of Late Gadolinium Enhancement Cardiac Magnetic Resonance in Hypertrophic Cardiomyo
Objective To perform a meta-analysis of the predictive value of late gadolinium enhancement(LGE)cardiac magnetic resonan......
Effect of carvedilol in attenuating the acute myocardium infarction-induced myocardial fibrosis in r
Aim: Carvedilol, nonselective β-adrenoreceptor antagoruist, was shown protective effects against acute myocardium infar......
Inhibition of Rho-kinase ameliorates myocardial remodeling and fibrosis in pressure overload and myo
Aim: Inhibition of Rho-kinase displays vasodilation property although its effect on cardiac remodeling in heart against ......
Activation of the complement system was related withthe inflammatory response after myocardial infar
Objective To investigate the role of activated complement system after myocardial infarction in mice.Methods Themodel of......
The effect of activation of ALDH2 on high concentration of glucose induced myocardial fibrosis in ca
The aim of our study was to observe whether ALDH2 is expressed in cardiac fibroblasts and investigate the effect of acti......
To observed the effect of EGb 761 against myocardial fibrosis and its mechanisms.After exposure to aldosterone and EGb 7......
Inhibition of Rho-kinase ameliorates myocardial remodeling and fibrosis in pressure overload and myo
Inhibition of Rho-kinase displays vasodilation property although its effect on cardiac remodeling in heart against press......
Icariin Ⅱ attenuates myocardial fibrosis by down-regulating TGF-β1/Smad2 signaling pathway in sponta
Objective: To investigate the effects of icariin Ⅱ (IRS) on myocardial fibrosis in spontaneously hypertensive rats (SHR......
RESEARCH ON EFFECT OF AGEs-RAGE SIGNALING PATHWAY ON MYOCARDIAL FIBROSIS OF TYPE TWO DIABETIC RATS A
Diabetic cardiomyopathy (DCM) is one of the chronic complications of diabetes mellitus (DM), and it is one of the main r......
Upregulation of miR-29b contributes to the anti-fibrotic effect of macrophage migration inhibitory f
Background Macrophage migration inhibitory factor (MIF) possesses proinflammatory function when secreted from the cells,......
Objective: To observe the dynamic changes of myocardial collagen metabolism in autoimmune myocarditis rats.Methods: We e......
The effects of Fuzheng Huayu(FZHY) capsule in improving myocardial fibrosis and remodeling following
Objective To determine the effects of Fuzheng Huayu (FZHY) capsule in improving myocardial fibrosis and remodeling follo......
Sang-qi Granula Reduces Blood Pressure and Myocardial Fibrosis by Suppressing Inflammatory Responses
Aim: Sang-qi Granula (SQ) is a compound preparation of Chinese medcine and currently used for treatment of hypertension ......
Association between left ventricular twist mechanics and myocardial fibrosis in hypertrophic cardiom
Aims: Late gadolinium enhancement (LGE) on contrast-enhanced magnetic resonance imaging (MRI) in hypertrophic cardiomyop......
目的 观察心脏糜酶对自发性高血压大鼠(SHR)心肌纤维化的影响及其作用机制.方法 实验动物分为对照WKY 组、SHR 组和SHR 应用糜酶抑......
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目的探讨2型糖尿病大鼠缺血预处理(IPC)对心肌缺血再灌注损伤(MIRI)的保护作用是否受到糖尿病心肌纤维化的影响。方法建立2型糖尿病大......
目的探讨microRNA对小鼠放射性心脏损伤(RIHD)的调节作用,为其治疗提供一个新策略。方法基于Gene Expression Omnibus数据库的GSE14......
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目的初步观察维生素C(Vit C)和三磷酸腺苷(ATP)对大鼠心肌纤维化的干预效果。方法选取雄性SD大鼠40只,体重为125~140 g,按大鼠体重采用随......
目的:本实验探讨HDAC 6在ISO诱导的大鼠心肌纤维化动物模型中表达机制。方法将SD大鼠随机分为两组,每组各20只。设正常组和模型组。......
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Effect of Sini decoction on angiotensin Ⅱ, transforming growth factor β1 and connective tissue growt
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目的观察黄精多糖(PSP)对糖尿病心肌病大鼠心肌纤维化影响,探讨其可能机制。方法健康雄性SD大鼠,随机分为对照组、模型组、黄精多......
心肌纤维化与心力衰竭、心律失常以及心源性猝死等密切相关.预防和逆转心肌纤维化是临床研究的热点之一.心肌纤维化的发病机制还未......
目的 应用超声背向散射测定结合胶原代谢物评估犬心肌缺血再灌注致心肌纤维化程度.方法 12只成年杂种犬随机分为2组:假手术组和缺......
心肌纤维化是心肌正常组织结构中出现的以成纤维细胞增殖、胶原过度沉积及异常分布为主要表现的病变。微小核糖核酸(miRNAs)是一类内......
糖尿病是一种累及全身多器官的慢性疾病,对心血管系统的影响尤为明显。细胞氧化损伤、脂代谢障碍以及细胞外基质沉积等病理改变均参......
Apelin是一种较新的心血管活性调节物质,在多种心血管疾病中扮演着重要角色,但其与心房颤动之间的关系报道较少,而心房颤动作为常......
心肌纤维化是临床上多种心脏疾病共同经历的一种病理过程,对心脏细胞重构、心脏的电传导、心功能等都有很大的影响。微小RNA是一类......
经皮主动脉瓣膜植入术可作为重度主动脉狭窄外科手术治疗高危患者的备选治疗方案。心血管影像在经皮主动脉瓣膜植入术的成功实施中......
MicroRNA是一组小分子单链RNA,其在转录后水平参与基因表达调控.近年来,microRNA在心血管疾病中的研究日益丰富,对其认识也日趋完......
心肌纤维化是以成纤维细胞分泌的胶原蛋白等细胞外基质过度沉积为特征的心血管疾病晚期表现.整合素β1作为一种跨膜黏附分子,在“......
Objective:To explore the protective effects of ginseng mixture on myocardial fibrosis(MF) in rats.Methods:A total of60Wi......
Toll样受体(TLRs)是一类介导固有免疫反应,具有Ⅰ型跨膜蛋白并能识别大量外源性配体的重要受体.TLRs不仅能够抵抗病原微生物的入侵......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
目的探讨胶原特异性分子伴侣一热休克蛋白47(HSP47)在心房颤动(房颤)的发生和维持中的作用。方法60例行心脏手术的患者分为3组,其中窦性......
目的:通过观察血清脂联素(APN)水平与慢性心力衰竭(CHF)大鼠心肌纤维化的关系,探讨APN在心肌纤维化发生、发展中的作用。方法:采用肾上腹......